Letcombe Regis is a village and civil parish in the Vale of White Horse. It was part of Berkshire until the 1974 boundary changes transferred the Vale of White Horse to Oxfordshire. The village is on Letcombe Brook at the foot of the Berkshire Downs escarpment about 1 mile (1.6 km) southwest of the market town of Wantage. The 2011 Census recorded the parish population as 578.